Autism spectrum disorder, or ASD, is a neurodevelopment disorder characterized by impaired social interaction and communication, as well as restrictive, repetitive patterns of behavior, interests, and activities. Clinical trials have demonstrated that sulforaphane from broccoli sprouts reduces the characteristic behaviors
Posts By: Teresa Johnson
Timing is Everything
One of the primary mechanisms by which sulforaphane and other isothiocyanates exert their many beneficial effects on the body is through activation of nuclear erythroid-2-p45-related factor-2, or Nrf2, the master regulator of cellular defenses that protect against oxidative stress due
Profiles in Chemoprotection: Part II
Albena Dinkova-Kostova, PhD
Before Albena Dinkova-Kostova, Ph.D. trained to become a scientist, she trained as a seamstress.
She was 16 years old and living in Ruse, a large cosmopolitan city located on the south bank of the Danube River in
New method for extracting the beneficial compounds in moringa identified
A team of researchers from the Cullman Chemoprotection Center at Johns Hopkins University and the Universidad Nacional Autónoma de México led by Dr. Jed Fahey has developed a convenient and household-friendly method of extracting the beneficial compounds present in moringa,
Dose matters: New research demonstrates that sulforaphane from broccoli sprouts combats a cause of air pollution injury in a dose-dependent manner
Air pollution contains many toxic substances. One of these substances, benzene, is known to cause cancer in humans. A new study led by the Cullman Chemoprotection Center’s scientific partner, Dr. Tom Kensler, found that sulforaphane provided in a broccoli
The plant enzyme that helps make broccoli so good for you survives the acid in your stomach
A team of scientists led by Dr. Jed Fahey of the Cullman Chemoprotection Center investigated whether stomach acidity influences the activity of myrosinase, a type of enzyme. Myrosinase plays a role in the production of sulforaphane, a beneficial plant compound
Profiles in Chemoprotection, Part I
Thomas Wells Kensler, PhD
In a makeshift greenhouse comprised of steel growing racks, plastic tarps, and a portable electric space heater, …colleagues Jed Fahey and Tom Kensler grew broccoli sprouts for a clinical trial to gauge sulforaphane bioavailability in humans.