Monthly Archives: July 2018

More Exciting Clinical Work on Broccoli Sprouts and Inflammation

Reducing inflammation may improve the health of overweight people by reducing inflammation and thus reducing the multitude of side-effects that go along with that inflammation. Incorporating broccoli sprouts or supplements rich in their biologically active phytochemicals into a regular diet could be beneficial.  The anti-inflammatory effects of phytochemicals glucoraphanin and sulforaphane are outlined in a recent… Read more »

Exciting Recent Paper on Inflammation and Nrf2

Long time Center member Dr. Dinkova-Kostova participated in research described in a very exciting paper in Nature that she co-authored along with a large team of colleagues from Harvard (US), Trinity College (Ireland), the Universities of Dundee, Cambridge, and Glascow (all UK), and elsewhere. Their study describes discovery of a Krebs cycle derivative that is a crucial anti-inflammatory metabolite which also regulates type… Read more »

Sulforaphane and Epilepsy

Cullman Chemoprotection Center members Drs. Dinkova-Kostova and Dayalan Naidu participated in a fascinating study recently published in the journal Brain, showing that increasing the body’s antioxidant defenses was protective against epilepsy in an animal model. They tested this novel strategy to increase endogenous antioxidant defenses using RTA 408, a drug synthesized by Reata Pharmaceuticals that… Read more »

New Study from Korea: Sulforaphane Has Positive Effects in a Mouse Model of Alzheimer’s Disease

Sulforaphane, was isolated by us from broccoli and broccoli sprouts many years ago.  It was developed by us and many others around the world as a chemoprotective phytochemical — a compound from plants that is not required for life (like proteins, carbohydrates, fats, vitamins and minerals), but which enhances health.  Many laboratory and animal studies… Read more »